Category: type 1 diabetes

Media coverage of blood spot testing

Media coverage of Type1Screen’s blood spot testing

The at home test kit for type 1 diabetes through Type1Screen has received significant attention this Diabetes Month! This was boosted substantially with thanks to the McCaughley Family.

Lila McCaughley was diagnosed with type 1 diabetes at the age of 9 in DKA (ketoacidosis – a life threatening state where blood sugar levels are too high because the pancreas can no longer produce insulin). In response, her mother Ange Liston-McCaughley founded the Type1Foundation to raise awareness around the signs and symptoms of type 1 diabetes to prevent as many other children as possible experiencing the same horrible diagnosis.

Ange has said that Type1Screen aligns with the values of the Type1Foundation because we too want to identify children and young people at the earliest stages of type 1 diabetes. Screening has been shown to prevent DKA, improve longer term diabetes management, and offers the opportunity for any available clinical trials to delay or prevent type 1 diabetes.

Lila McCaughley and her little brothers

So when Ange decided to get herself, and the rest of her family screened for type 1 diabetes using the new at home blood spot test with Type1Screen, the type 1 diabetes community took notice! And so too did the media. Thanks to the McCaughley family for their ongoing support and their amazing media skills!

For all the media coverage you can click on these links:

Community Engagement Panel – ATIC

Community Engagement Panel Members sought for ATIC

The Australasian Type 1 Diabetes Immunotherapy Collaborative (ATIC) brings together researchers, clinicians and advocates to identify and create immunotherapy clinical trial opportunities for people at every age and every stage of type 1 diabetes (T1D).

Supported by JDRF Australia, ATIC is led by St Vincent’s Institute of Medical Research (SVI) in Melbourne and involves multiple major type 1 diabetes centres across Australia and New Zealand.

Core to ATIC’s success is involvement of the broader type 1 diabetes community – people living with the condition, their families and advocates. People with first-hand experience of T1D are sought to join the ATIC Community Engagement Panel.

If you’re passionate about improving the lives of people with type 1 diabetes through immunotherapy research and ultimately treatments to delay and prevent T1D, don’t miss your chance to be a part of this exciting opportunity.

Applications are being accepted until COB Friday 2 December.

More information is available on the ATIC website:

Community Engagement Panel – calling for expressions of interest

Screening for Type 1 Diabetes decreases ketoacidosis and preserves beta cell function

Screening for Type 1 Diabetes decreases ketoacidosis and preserves beta cell function

A recent paper authored by our lead Type1Screen clinicians has demonstrated clearly that screening relatives for Type 1 Diabetes decreases ketoacidosis and preserves beta cell function for those in identified in the earliest stages of T1D.

You can read the full paper here and listen to John Wentworth being interviewed about it here.

Thanks to the amazing McCaughley Family for supporting the bloodspot screening program by getting their whole family tested and sharing the experience online and via the Herald Sun.

100 registrations!

Type1Screen registers 100 participants!

Type1Screen has registered its 100th participant via our new online portal.

The portal was launched on July 28th 2022. Our very first registrant joined August 18th 2022.

We are really pleased and thankful for the community uptake of this initiative.

If there is type 1 diabetes in your family, and you wish to get screened for your risk of the condition, you can register here.

Anyone aged 2 years or older with a family history of type 1 diabetes, and living in Australia or New Zealand, is eligible for this free screening test.

These two siblings participated in Type1Screen because their mum has Type 1 Diabetes.

How do I do a blood spot test?

How do I do a blood spot test?

So you have a family member diagnosed with type 1 diabetes, and you’ve heard about the new and easy finger prick blood spot test you can do at home. This test will help to assess your, or your child’s, risk for type 1 diabetes.

OK, it sounds easy, but can I really do it myself at home?

Dr John Wentworth will show you how in this short video.

ATIC

ATIC

The Australasian Type 1 Diabetes Immunotherapy Collaborative (ATIC) officially launched at the Australasian Diabetes Congress in Brisbane on the 10th August 2022.

The ATIC Team from L-R: Dr Michelle So, A.Prof. John Wentworth, Dr Michaela Waibel, Prof. Tom Kay, Prof Helen Thomas, Ms. Candice Hall.

What is ATIC?

The Australasian Type 1 Diabetes Immunotherapy Collaborative (ATIC) is a clinical trials network of adult and paediatric endocrinologists, immunologists, clinical triallists and members of the type 1 diabetes (T1D) community.

Immunotherapies have been shown to blunt the immune attack on the pancreas that occurs in people with type 1 diabetes. ATIC’s work will discover the safest and most effective immunotherapy treatments.

The ATIC team are working across six domains with the bold vision to fast-track immunotherapy treatment options for people with type 1 diabetes.

  1. Clinical Trials: Implement immunotherapy trials for type 1 diabetes
  2. Community Engagement: Ensure ATIC’s work meets the needs of people living with type 1 diabetes
  3. Pre-clinical & Translation: Help transform scientific discoveries into effective treatments
  4. Data management: Facilitate data driven research
  5. Education and training around the fundamentals of immunotherapy, and the latest research on its use in type 1 diabetes
  6. Advocacy, regulation and government: Drive regulatory approval and government funding of immunotherapy treatments for type 1 diabetes.

ATIC facilitates immunotherapy clinical trials across a network of leading clinical trial centres. ATIC can advise on mechanisms for obtaining trial funding, assist with initial ethics approvals, oversee trial conduct, and support participant recruitment efforts to ensure clinical trials are delivered on time and within budget.

For more information, take a look at the new website at: https://atic.svi.edu.au/

Type1Screen has made screening simple

Edward proudly showing his bandaid after his fingerprick test

Type1Screen is entering a really exciting phase.

We have just rolled out finger prick tests that families can perform at home and mail back to our lab. Our new antibody assay allows us to get a result back to families a little sooner than the standard assay based on a formal blood collection.

Early diagnosis of type 1 diabetes is really important. It allows us to monitor children for signs of progression and, if this occurs, to start insulin injections in good time and prevent serious illness, which currently affects a third of our children. Not all positive screens progress quickly and in many cases we have time to offer opportunities to join immunotherapy prevention studies.

We really hope that the blood spot screening test will make it much easier for families to access screening, particularly those living in regional communities.

If you would like to see just how simple it is to get screened, please contact us to receive a kit to use at home. If you want to help us spread the word about this program, please tag us online @Type1Screen.

Ultimately, we want to make screening accessible to every Australian child. Type1Screen will take us closer to this goal by demonstrating to the world that we can perform cheap and accurate screening in a timely manner and at scale.

Brave Maeve did a fingerprick test at home with help from her mum

Trial for new T1D diagnosis

IMPACT Study for those newly diagnosed with T1D

Type1Screen is supporting the enrolment of young adults with a recent diagnosis of type 1 diabetes (T1D) to a new drug trial. This randomized, placebo-controlled, multi-centre clinical trial will evaluate the treatment of the Imotope™ IMCY-0098 and its effect on the preservation of beta-cell function in people with a recent onset T1D.

Aim

The study aims to investigate the effect of two doses of IMCY-0098 upon treatment-specific biomarkers and the effect of study medication on beta-cell function in adults with recently diagnosed type 1 diabetes.

Eligibility to take part

  • Aged 18 to 44 years
  • Diagnosed with type 1 diabetes (first insulin treatment) within 9 weeks of study screening visit.

How do I take part?

  • Contact Type1Screen via
    • email type1screen@mh.org.au
    • phone (03) 9342 7063

Type1Screen receives DARP funding

Type1Screen receives Diabetes Australia Research (DARP) funding

We’re grateful to Diabetes Australia for a generous grant to help us bring the home testing risk screening kits over the finish line and out to families.

A. Prof John Wentworth was interviewed recently by former professional Australian rules footballer, Jack Fitzpatrick, for the Diabetes Victoria podcasts. Jack lives with type 1 diabetes himself.

The interview discussed the advancement of risk screening for type 1 diabetes and the aim to identify people in the earliest stages of the condition as possible to:

1. offer current and emerging immunotherapy trials and treatments, and

2. avoid severe illness and hospitalisation

Hear the full interview here: https://www.diabetesvic.org.au/podcasts 

Thanks to the Lions Australia Diabetes Foundation

Thanks to the Lions Australia Diabetes Foundation

The earlier someone is diagnosed with diabetes, the more insulin-producing (beta) cells in the pancreas are preserved, providing an opportunity to slow or stop further destruction and ultimately prevent the need for insulin injections.

Associate Professor John Wentworth and our team are working to produce an in-home finger prick blood test to identify children destined to develop type 1 diabetes. Once validated, the screening test will identify those with the most to gain from preventative therapies and protect them from critical illness requiring admission to hospital.

We’re so grateful to have the support of the Lions Australia Diabetes Foundation for this project. Recently, Lion Harry Brindley ASM (pictured left) met with A/Prof Wentworth (right) at the Walter and Eliza WEHI to discuss the project and present a much-appreciated cheque for $28,750